The shape ofd-glucosamine

The shape of D-glucosamine.

The bioactive amino monosaccharide D-glucosamine has been generated in the gas phase via laser ablation of D-glucosamine hydrochloride. Three cyclic α-(4)C1 pyranose forms have been identified using Fourier transform microwave techniques. Stereoelectronic hyperconjugative forces - essentially linked with the anomeric or gauche effect - and cooperative OH···O, OH···N and NH···O chains, extended ...

The orofaciodigital (OFD) syndromes.

Observation ofD D Oscillations

We report a measurement of the time-dependent ratio of D ! Kþ to D ! K þ decay rates in D þ-tagged events using 1:0 fb 1 of integrated luminosity recorded by the LHCb experiment. We measure the mixing parameters x02 1⁄4 ð 0:9 1:3Þ 10 , y0 1⁄4 ð7:2 2:4Þ 10 , and the ratio of doubly-Cabibbo-suppressed to Cabibbo-favored decay rates RD 1⁄4 ð3:52 0:15Þ 10 , where the uncertainties include statistic...

Glucosamine.

Glucosamine is one of the most popular dietary supplements sold in the United States. Most clinical trials have focused on its use in osteoarthritis of the knee. The reported adverse effects have been relatively well studied and are generally uncommon and minor. No significant supplement-drug interactions involving glucosamine have been reported. The National Institutes of Health-sponsored Gluc...

Glucosamine Metabolism

Recent studies in this laboratory, concerned with hexosamine metabolism, required Gm-6-P,’ Galm-BP, and their respective N-acetyl derivatives. Several methods are available for the preparation of Cm-6-P, but there appears to be no previous report of Calm-6-P, although an acid-stable Galm-P has been isolated from cartilage (4). Earlier reports indicated that hexokinase and ATP would phosphorylat...